ProLiant ML350 Gen11 Server
The HPE ProLiant ML350 Gen11 is the current dual-socket tower — 4th Gen Xeon Scalable with DDR5, PCIe Gen5, and GPU options in a quiet, expandable chassis.
The HPE ProLiant ML350 Gen11 is the current dual-socket tower — 4th Gen Xeon Scalable with DDR5, PCIe Gen5, and GPU options in a quiet, expandable chassis.
The HPE ProLiant ML350 Gen11 Server is a powerful and highly expandable tower server designed for businesses that need enterprise-class performance, flexible storage, scalable memory, and long-term reliability in an office-friendly platform. Built for small to mid-sized businesses, remote offices, branch locations, data centers, virtualization, databases, backup, file storage, AI, machine learning, and business-critical applications, the ML350 Gen11 delivers strong dual-socket Intel Xeon performance with modern DDR5 memory and PCIe Gen5 expansion. This Build Your Own platform gives you the flexibility to configure the server with the processors, memory, storage, RAID, networking, GPU options, and operating system that best fit your environment.

The HPE ProLiant ML350 Gen11 features a tower chassis designed for businesses that need room to grow while maintaining a practical office-friendly form factor. It is well suited for offices, back rooms, branch locations, remote sites, and growing IT environments where a traditional rackmount server may not be required. For organizations that later move toward rack infrastructure, the ML350 Gen11 also offers rack conversion capability, giving businesses flexibility as their deployment needs change.
The HPE ProLiant ML350 Gen11 supports 4th and 5th Generation Intel Xeon Scalable processors, giving businesses access to strong compute performance for demanding workloads. With support for up to 64 cores per processor, the ML350 Gen11 can deliver up to 128 cores per server depending on configuration. This makes it a strong fit for virtualization, database hosting, application hosting, analytics, AI, machine learning, business processing, and other workloads that need scalable multi-core performance.
The ProLiant ML350 Gen11 supports DDR5 memory, offering improved bandwidth and efficiency compared to previous-generation DDR4 platforms. With support for up to 8TB of DDR5 memory depending on configuration, the ML350 Gen11 can be built for memory-intensive workloads such as virtualization, databases, analytics, caching, VDI, and business-critical applications. This memory scalability helps businesses support larger workloads while maintaining stable and responsive system performance.
The HPE ProLiant ML350 Gen11 offers flexible storage options to support a wide range of business needs. Depending on the selected chassis and backplane, the system can be configured with large form factor drives, small form factor drives, SSDs, NVMe storage, or EDSFF storage options. This flexibility allows the ML350 Gen11 to be built for high-capacity local storage, fast SSD performance, backup repositories, database storage, virtualization datastores, file sharing, or mixed storage environments. Compatible HPE Smart Array and HBA controller options can help provide storage performance, redundancy, and data protection.
The ML350 Gen11 supports PCIe Gen5 expansion, giving businesses room for high-speed network adapters, storage controllers, graphics cards, accelerators, and other compatible PCIe devices depending on configuration. This makes the system a strong option for businesses that need flexible I/O, faster networking, improved storage performance, or GPU acceleration. HPE positions the ML350 Gen11 for workloads that may require enhanced I/O and GPU support, making it useful for AI, machine learning, analytics, visualization, and specialized business applications.
The HPE ProLiant ML350 Gen11 includes HPE Integrated Lights-Out, commonly known as iLO, for remote server management. HPE iLO allows administrators to monitor system health, access management tools, perform maintenance, and troubleshoot the server remotely. This helps reduce hands-on service time, improves visibility, and simplifies administration for small IT teams, managed service providers, branch offices, and distributed environments where physical access to the server may be limited.
The ProLiant ML350 Gen11 is designed with HPE server reliability and security features to support dependable business operation. Depending on configuration, available features may include silicon root of trust, secure firmware protections, platform monitoring, TPM support, and remote management security through HPE iLO. Combined with enterprise storage options, ECC memory, redundant power supply options, and server-grade cooling, the ML350 Gen11 is built to support important business workloads with confidence.
The HPE ProLiant ML350 Gen11 is designed to deliver strong enterprise performance while remaining serviceable and adaptable. Its tower form factor provides room for storage, expansion cards, GPUs, memory growth, and serviceable components, making it a practical platform for businesses that expect their infrastructure needs to grow over time. For organizations looking for an expandable enterprise-class tower server, the ML350 Gen11 provides strong long-term value and flexibility.
The HPE ProLiant ML350 Gen11 Server is best suited for:
The HPE ProLiant ML350 Gen11 Server is a powerful, expandable, and flexible tower server built for businesses that need enterprise performance without sacrificing deployment flexibility. With support for 4th and 5th Gen Intel Xeon Scalable processors, DDR5 memory, PCIe Gen5 expansion, flexible storage options, GPU support, HPE storage controller options, and HPE iLO remote management, the ML350 Gen11 is well suited for virtualization, databases, backup, file storage, business applications, AI, analytics, and remote office workloads. Whether deployed as a tower server in an office environment or converted for rack use in a data center, the HPE ProLiant ML350 Gen11 provides dependable performance and scalability for modern business infrastructure.