ProLiant DL385 Gen10 Server
The HPE ProLiant DL385 Gen10 brings dual AMD EPYC processors to HPE's proven 2U platform — high core counts and 128 PCIe lanes for virtualization and storage-dense builds.
BYO HPE ProLiant DL385 Gen10 Server - 2U AMD EPYC Rack Server for Virtualization and Business Workloads
The HPE ProLiant DL385 Gen10 Server is a powerful 2U rack server designed for businesses that need dependable dual-socket AMD EPYC performance, flexible storage, scalable memory, and enterprise-class reliability. Built for virtualization, database hosting, software-defined storage, backup, analytics, VDI, private cloud, and general business infrastructure, the DL385 Gen10 delivers a strong balance of compute power, memory capacity, storage flexibility, and remote management. This Build Your Own platform gives you the flexibility to configure the server with the processors, memory, storage, RAID, networking, and operating system options that best fit your environment.
Versatile 2U Rackmount Design
The HPE ProLiant DL385 Gen10 features a 2U rackmount chassis designed for organizations that need strong compute performance, flexible storage capacity, and room for expansion. Its 2U form factor provides more space for drive bays, PCIe expansion, cooling, and serviceable components than compact 1U systems, making it a strong choice for data centers, small to mid-sized business server rooms, managed service providers, hosting environments, and growing IT infrastructures.
Dual-Socket AMD EPYC Performance
The HPE ProLiant DL385 Gen10 is built around AMD EPYC processor technology, offering strong core density, memory bandwidth, and multi-threaded performance for demanding workloads. With support for dual AMD EPYC processors depending on configuration, the DL385 Gen10 is well suited for virtualization, databases, analytics, VDI, application hosting, software-defined storage, and other workloads that benefit from high core counts and efficient server performance.
Memory
The ProLiant DL385 Gen10 supports enterprise-grade DDR4 ECC server memory designed for stable operation in production environments. ECC memory helps maintain data integrity and reliable system performance, which is important for always-on infrastructure and mission-critical workloads. With scalable memory configuration options, the DL385 Gen10 can be built for virtualization, database hosting, analytics, caching, software-defined storage, and memory-intensive business applications.
Storage Options and Flexibility
The HPE ProLiant DL385 Gen10 offers flexible storage configurations depending on the selected chassis and backplane. Available builds may include small form factor or large form factor drive layouts for SAS, SATA, HDD, SSD, and NVMe storage depending on configuration. This flexibility allows the DL385 Gen10 to be configured for high-capacity storage, fast SSD-based application storage, virtualization datastores, backup repositories, database storage, or mixed-use environments. HPE Smart Array RAID and HBA options can help provide storage performance, redundancy, and data protection for important business workloads.
Expansion and Connectivity
The 2U design of the ProLiant DL385 Gen10 provides expansion capability for compatible networking, storage controllers, HBAs, GPUs, and other PCIe-based hardware depending on the final build. This makes the DL385 Gen10 a flexible platform for organizations that need to support changing infrastructure needs, including faster networking, improved storage performance, additional I/O, or accelerator support for specialized workloads.
Network Connectivity
Reliable network connectivity is essential for modern IT infrastructure, and the HPE ProLiant DL385 Gen10 can be configured with embedded and add-in network options depending on the system build. Whether used for virtualization traffic, storage networking, backup, database access, web hosting, or application workloads, the DL385 Gen10 can be tailored with networking options that support the required level of throughput and redundancy.
Remote Management with HPE iLO 5
The HPE ProLiant DL385 Gen10 includes HPE Integrated Lights-Out 5, commonly known as iLO 5, for remote server management. HPE iLO allows administrators to monitor system health, access management tools, perform maintenance, and troubleshoot the server remotely, helping reduce hands-on service time and improve system visibility. This is especially valuable for small IT teams, managed service providers, data centers, and distributed environments where physical access to the server may be limited.
Security and Reliability
The ProLiant DL385 Gen10 is designed with HPE server reliability and security features to help support dependable business operation. Depending on configuration, available features may include silicon root of trust, secure firmware protections, TPM support, platform monitoring, and secure management tools through HPE iLO. Combined with enterprise memory, HPE storage options, RAID support, redundant power supply options, and server-grade cooling, the DL385 Gen10 is built to support daily business workloads with confidence.
Energy Efficiency and Serviceability
The HPE ProLiant DL385 Gen10 is designed to deliver strong dual-socket compute performance in a practical and serviceable 2U platform. Its layout provides room for configurable storage, expansion options, efficient airflow, and accessible components, making it a strong fit for organizations that need both performance and maintainability. For businesses looking for a refurbished enterprise server with AMD EPYC performance and flexible configuration options, the DL385 Gen10 offers excellent long-term value.
Ideal Use Cases
The HPE ProLiant DL385 Gen10 Server is best suited for:
- Virtualization: A strong dual-socket AMD EPYC platform for VMware, Hyper-V, and other virtualization environments when configured with appropriate CPU, memory, and storage.
- Database Workloads: Core density, memory scalability, and flexible storage make the DL385 Gen10 suitable for database hosting and data-driven applications.
- Software-Defined Storage: Flexible drive configurations and enterprise RAID or HBA options make the DL385 Gen10 useful for storage-heavy deployments.
- Backup and File Storage: SFF and LFF storage options make the system a strong fit for backup repositories, file shares, and local data retention.
- VDI and Private Cloud: Strong compute and memory capabilities make the DL385 Gen10 useful for virtual desktop infrastructure and private cloud environments.
- Business Application Hosting: A dependable 2U platform for internal applications, web services, analytics, and production workloads.
Conclusion
The HPE ProLiant DL385 Gen10 Server is a powerful and flexible 2U rack server built for businesses that need AMD EPYC performance, scalable memory, configurable storage, remote management, and enterprise reliability. With dual-socket AMD EPYC processor support, DDR4 ECC memory, flexible SAS, SATA, SSD, and NVMe storage options depending on build, HPE Smart Array storage support, and HPE iLO 5 management, the DL385 Gen10 is well suited for virtualization, databases, software-defined storage, backup, VDI, private cloud, and general business infrastructure. Whether deployed in a data center, branch office, managed service environment, or growing business network, the HPE ProLiant DL385 Gen10 provides dependable server performance in a cost-effective refurbished enterprise platform.
HPE ProLiant DL385 Gen10 Server Spec Sheets
HPE ProLiant DL385 Gen10 QuickSpecs.pdf
HPE ProLiant DL385 Gen10 User Guide.pdf
HPE ProLiant DL385 Gen10 Maintenance and Service Guide.pdf
HPE ProLiant DL385 Gen10 Technical Specifications.pdf